Join Our Mission to Translate Cutting-Edge Research into Life-Changing Therapeutics

We (the group of Prof. Andreas Moor at the Department of Biosystems Science and Engineering of ETH Zurich, located in Basel) are currently seeking a visionary scientist to join our team and drive antibody and nanobody-based drug discovery (start immediately or by arrangement). This position is ideal for a researcher with a background in biotechnology, molecular biology, or related fields, who is eager to transform pioneering research into practical, patient-focused solutions. 

In this role, you will work at the convergence of fundamental research and translational development- advancing antibodies and nanobodies from early discovery toward therapeutic applications. Your responsibilities will include initial discovery, rigouros screening, and detailed characterization of novel protein binders aimed at disease-relevant targets, in an environment that values both scientific excellence and strategic application

We welcome candidates with a Master's (MSc) or PhD in Biotechnology or a related field who are eager to apply their expertise to impactful challenges. Prior experience with protein engineering, display technologies (phage, yeast, or ribosome display), or cell-based assays is advantageous.

• Experimentation : Design and execution studies to develop and characterize novel antibodies and nanobodies.
• Optimization : Apply molecular biology and protein engineering techniques to enhance binders for affinity, specificity, and stability.
• Assay Development: Create and validate cell-based assays to assess therapeutic potential.
• Collaborative Innovation:   work alongside interdisciplinary teams, including clinical and industry experts, to advance discoveries from bench toward preclinical applications.
• Strategic Development: Contribute to initiatives related to technology transfer, intellectual property, and the evolution of our therapeutic pipeline.

Qualifications

• A Master's degree or PhD degree in the relevant field with a proven track record of hands-on experience in the workflows and protocols relevant for the position
• Excellent interpersonal skills and creativity, “out of the box” thinking
• Ability to operate under pressure and deliver results within specified timelines and budgets

Areas of technical expertise include

• Protein engineering
• Protein purification
• Fluorescent microscopy, flow cytometry, cell sorting
• ELISA and BLI assays
• Display assays (phage, yeast, or ribosome)
• Mammalian cell culture
• Regulatory experience or prior drug development exposure is a plus
• Animal experimentation experience is a plus

This role is tailored for scientists who

• Are passionate about antibody and nanobody-based therapeutics.
• Aspire to see innovative research evolve into tangible clinical solutions.
• Value a collaborative setting where scientific inquiry meets strategic development (i.e. spinoffs, startups, and commercialization).
• Thrive in a dynamic environment that bridges discovery with practical impact. 

• Join a pioneering research team that is shaping the future of biotherapeutics.
• Gain hands-on experience in translational science and drug development.
• Collaborate in an interdisciplinary environment alongside academic and industry experts.
• Play a key role in developing intellectual property and fostering potential spinoff ventures.
• Embrace the challenge of advancing novel therapeutics from the lab to patient care.

We look forward to receiving your online application with the following documents:

• Cover letter (Which of your research projects was most exciting to you so far and why? Why would you like to join us?)
• CV
• relevant certificates
• Names of 3 references 

Please note that we exclusively accept applications submitted through our online application portal. Applications via email or postal services will not be considered.

Further information about the laboratory, can be found on our webpage . For more information about the position, contact Prof. Andreas Moor ( andreas.moor@bsse.ethz.ch ) (no applications).