Phd Student Position in Development of Protocols for Isolation of Microbial Strains for Sustainable Protein Production 100%, Basel, fixed-term We develop technologies to exploit whole cell and enzyme catalysts for manufacturing of substances for applications in fields such as sustainable chemistry, innovative food, or active pharmaceutical ingredients. For a third-party funded project in the sector of innovative, non-agricultural food aiming at microbial manufacturing of proteins from reactive gases, we are offering a position for a PhD student. Project background The project is embedded into the EC-sponsored consortium HydroCow with partners from the UK, German, and Finland covering competences in metabolic flux modelling, molecular engineering, manufacturing and marketing. For HydroCow, we are building on an earlier developed ultra-high-throughput screening platform that allows for the rapid identifying of improved industrial production strains. At the heart of this platform are microcolonies grown in gel-capsules, which are subjected to fluorescence-based analysis for quantification of the product of interest. This technology will now be adopted for secretion recombinantly synthesized proteins for the first time. Job description The PhD-Student will perform the following tasks: Development of high throughput assays, typically based on fluorescence mediated by biosensors or (bio)chemicals Characterization of assay performance using lead strains Execution of large-scale screening campaigns with up to 1E6 variant strains Co-representation and reporting of BPL results in consortium meetings Co-coordination of tasks with all consortium partners Profile Master in molecular biology, microbiology or industrial biotechnology Good communication (in English) and teamwork skills We are also looking for all or a subset of the following additional qualifications:Prompt availability and commencement of employment are advantageous A solid background in chemistry and spectrometric analyses Development protocols from scratch (as opposed to implementing commercial kits) Working under atmosphere control (e.g., glove boxes) Workplace We offer We are offering An intellectually challenging position in the inspiring atmosphere of an interdisciplinary team Multifaceted, applied work in a larger international team with academia and industy Develop of technologies and protocols that will find commercial applications Development of personal skills including writing, presentation and project management Possibility to work with and supervise students Participation at international conferences and project workshops chevron_right Working, teaching and research at ETH Zurich We value diversity and sustainability In line with our values, ETH Zurich encourages an inclusive culture. We promote equality of opportunity, value diversity and nurture a working and learning environment in which the rights and dignity of all our staff and students are respected. Visit our Equal Opportunities and Diversity website to find out how we ensure a fair and open environment that allows everyone to grow and flourish. Sustainability is a core value for us – we are consistently working towards a climate-neutral future. Curious? So are we. We look forward to receiving your online application with the following documents: Letter (max. 1 A4) describing your background, interest and motivation CV Certificates (transcripts for Master degree) Two reference letters Further information about BPL and D-BSSE can be found on our website. Questions regarding the position should be directed by email to Martin.Held@bsse.ethz.ch (no applications). Please note that we exclusively accept applications submitted through our online application portal. Applications via email or postal services will not be considered. We would like to point out that the pre-selection is carried out by the responsible recruiters and not by artificial intelligence. About ETH Zürich ETH Zurich is one of the world’s leading universities specialising in science and technology. We are renowned for our excellent education, cutting-edge fundamental research and direct transfer of new knowledge into society. Over 30,000 people from more than 120 countries find our university to be a place that promotes independent thinking and an environment that inspires excellence. Located in the heart of Europe, yet forging connections all over the world, we work together to develop solutions for the global challenges of today and tomorrow. Wenn Sie sich auf diese Stelle bewerben, erwähnen Sie bitte dass Sie sie auf Universitoxy gesehen haben.

Phd Student Position in Development of Protocols for Isolation of Microbial Strains for Sustainable Protein Production

100%, Basel, fixed-term

We develop technologies to exploit whole cell and enzyme catalysts for manufacturing of substances for applications in fields such as sustainable chemistry, innovative food, or active pharmaceutical ingredients.

For a third-party funded project in the sector of innovative, non-agricultural food aiming at microbial manufacturing of proteins from reactive gases, we are offering a position for a PhD student.

Project background

The project is embedded into the EC-sponsored consortium HydroCow with partners from the UK, German, and Finland covering competences in metabolic flux modelling, molecular engineering, manufacturing and marketing.

For HydroCow, we are building on an earlier developed ultra-high-throughput screening platform that allows for the rapid identifying of improved industrial production strains. At the heart of this platform are microcolonies grown in gel-capsules, which are subjected to fluorescence-based analysis for quantification of the product of interest. This technology will now be adopted for secretion recombinantly synthesized proteins for the first time.

Job description

The PhD-Student will perform the following tasks:

Development of high throughput assays, typically based on fluorescence mediated by biosensors or (bio)chemicals
Characterization of assay performance using lead strains
Execution of large-scale screening campaigns with up to 1E6 variant strains
Co-representation and reporting of BPL results in consortium meetings
Co-coordination of tasks with all consortium partners

Profile

Master in molecular biology, microbiology or industrial biotechnology
Good communication (in English) and teamwork skills
We are also looking for all or a subset of the following additional qualifications:Prompt availability and commencement of employment are advantageous
1. A solid background in chemistry and spectrometric analyses
2. Development protocols from scratch (as opposed to implementing commercial kits)
3. Working under atmosphere control (e.g., glove boxes)

Workplace

We offer

We are offering

An intellectually challenging position in the inspiring atmosphere of an interdisciplinary team
Multifaceted, applied work in a larger international team with academia and industy
Develop of technologies and protocols that will find commercial applications
Development of personal skills including writing, presentation and project management
Possibility to work with and supervise students
Participation at international conferences and project workshops

chevron_right Working, teaching and research at ETH Zurich

We value diversity and sustainability

In line with our values, ETH Zurich encourages an inclusive culture. We promote equality of opportunity, value diversity and nurture a working and learning environment in which the rights and dignity of all our staff and students are respected. Visit our Equal Opportunities and Diversity website to find out how we ensure a fair and open environment that allows everyone to grow and flourish. Sustainability is a core value for us – we are consistently working towards a climate-neutral future.

Curious? So are we.

We look forward to receiving your online application with the following documents:

Letter (max. 1 A4) describing your background, interest and motivation
CV
Certificates (transcripts for Master degree)
Two reference letters

Further information about BPL and D-BSSE can be found on our website. Questions regarding the position should be directed by email to Martin.Held@bsse.ethz.ch (no applications).

Please note that we exclusively accept applications submitted through our online application portal. Applications via email or postal services will not be considered.

We would like to point out that the pre-selection is carried out by the responsible recruiters and not by artificial intelligence.

About ETH Zürich

ETH Zurich is one of the world’s leading universities specialising in science and technology. We are renowned for our excellent education, cutting-edge fundamental research and direct transfer of new knowledge into society. Over 30,000 people from more than 120 countries find our university to be a place that promotes independent thinking and an environment that inspires excellence. Located in the heart of Europe, yet forging connections all over the world, we work together to develop solutions for the global challenges of today and tomorrow.

Wenn Sie sich auf diese Stelle bewerben, erwähnen Sie bitte dass Sie sie auf Universitoxy gesehen haben.

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